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COVID-19 ADVISORY

We know all of our customers are concerned about COVID-19 (Coronavirus). We want to assure you that we are maintaining normal business hours to meet all of your prescription and over-the-counter needs. We are also sanitizing our counters and credit card area thoroughly throughout the day. We appreciate you supporting your local pharmacy. Thank you!

  • Main Street Pharmacy

    Main Street Pharmacy

    Your Local Health And Wellness Pharmacy

  • Compounding

    Compounding

    Need a special medication? We specialize in custom compounding

  • Free Delivery

    Free Delivery

    Let us come to you

  • Medication Synchronization

    Medication Synchronization

    Pick up all of your medications on the same day each month

  • Pet Care

    Pet Care

    Specialized compounding for your family pet

  • Greeting Cards

    Greeting Cards

    Birthday, Anniversary, or Special Celebration? We've got a card for that!

  • Text Notification Service

    Text Notification Service

    Ask our friendly staff about our text notification service

  • CBD

    CBD

    Carrying a Full-line of CBD Products!

Refill a Prescription

We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.

Refill Now

Transfer a Prescription

Transfer your prescriptions to our pharmacy using our simple and secure online transfer form.

Transfer Now

Contact Us

Visit us in store or get in touch with a member of our pharmacy staff. We're always happy to assist you.

Get in Touch

Your Partners In Health

Main Street Pharmacy Services

Become a Pharmacy Insider

Subscribe to our newsletter for promotions, health news and savings

Our Services

Your One Stop Shop

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Medication Synchronization

Speak to a staff member today about how we can get you set up on med sync.

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Easy Prescription Filling

We fill new and existing prescriptions in-store, by phone, online, and with our mobile app.

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Express Delivery

We offer express local delivery and shipping at no cost to you.

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Medication Savings

Our pharmacists work with you to coordinate benefits and find financial assistance.

Your Pharmacy Experts

Trust Us With Your Health

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At Main Street Pharmacy, we believe that being a local independent pharmacy means providing healthcare and compounding services to our patients that are customized to meet their needs. Visit us today and let us take care of you.



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Your health information in one place.

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Read Our Patient Reviews

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Carla R.

"A true community pharmacy with knowledgeable, caring owners and staff. Customer focused and friendly."

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Bill L.

"I am 93 years old, and I have never been treated with so much kindness and compassion that I have received from the staff at Main Street pharmacy in Safety Harbor. They make you feel like you are their only customer"

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Taylor B.

"The staff went above and beyond to help me get the right medication (after my doctor’s office sent them the wrong script). They provided excellent customer service and I will certainly be a repeat customer."

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Learn About Us »

Main Street Pharmacy combines high quality products with personalized care. Our staff is happy to help you with any questions you may have.

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Explore Our Health News »

Check out our weekly health news blog, or subscribe to our newsletter and receive updates on health articles, promotions, specials and much more.

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Find Services »

We offer a wide variety of services including conventional prescription filling, compounding, pet care, medication synchronization and much more.

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We'd Love To Hear From You

  • At Main Street Pharmacy, we’re committed to helping you live a healthier life. Our pharmacy staff would be happy to help you with any questions you may have.